Materials for Containers Bottles & Carboys

Material Choices for Nalgene® Bottles & Carboys

An Original Equipment Manufacturer’s (OEM) design may require a modification to a plastic bottle or carboy such as drilling holes in the cap or perhaps marking or labeling the bottle in some way. Piedmont CMG is able to acquire any plastic bottle or carboy that is readily available from a manufacturer or distributor and make the required modifications to the customer’s exact specifications.

Highest Quality Material Sources

Piedmont CMG sources our bottles and carboys from Thermo Scientific™ Nalgene™. Nalgene™ bottles are the #1 choice for bottles and carboys used in the Life Sciences industry. They are made in the USA using the highest quality plastic resins that meet pharmaceutical and laboratory grade standards.

Three Custom Clinical Diagnostic Fluidic Storage Bottles Made of Different Materials

Nalgene bottles and carboys contain far lower concentrations of trace element extractables and potential leachables than glass and they are a safe and shatterproof alternative to glass.

Nalgene offers containers for virtually any application and they are made from a variety of plastic types. HDPE, LDPE, PP and FLPE bottles are available for chemical resistance. If sterilization is a requirement, autoclavable PC, PP, and PMP bottles are an option. For maximum chemical resistance and tolerance to temperature PFA and FEP bottles are offered.

High Quality Plastic Resin Advantages


Low-Density Polyethylene (LDPE)

  • High Molecular Weight Hydrocarbon
  • No Known Solvent at Room Temperature
  • Chemically Inert

High-Density Polyethylene (HDPE)

  • High Molecular Weight Hydrocarbon
  • No Known Solvent at Room Temperature
  • Chemically Inert
  • More Rigid and Less Permeable than LDPE

Polypropylene (PP)

  • Autoclavable
  • No Known Solvent at Room Temperature
  • Best Stress Crack Resistance of the Polyolefins

Polymethylpentene (PMP)

  • Autoclavable (Withstands Repeatable Autoclaving)
  • Excellent High Temperature and Chemical Resistance
  • Excellent Transparency and Rigidity

Engineering Resins

Polycarbonate (PC)

  • Autoclavable
  • Window Clear
  • Amazingly Strong and Rigid
  • Non-Toxic
  • Toughest of All Thermoplastics

Polyethylene Terephthalate G Copolymer (PETG/PET)

  • Glass-Like Clarity
  • Excellent Gas-Barrier Properties
  • Outstanding for Storing Biologicals
  • Non-Cytotoxic
  • Sterilization with Radiation or Compatible Chemicals

Sterilization of Containers

Autoclaving is the preferred method for sterilizing Nalgene containers made of select resins.

Autoclavable resins include:

  • Polycarbonate
  • Polymethylpentene
  • Polypropylene
  • Polypropylene Copolymer
  • Teflon FEP and Teflon PFA

DNase and RNase enzymes break down DNA and RNA. They are contaminants that can interfere with nucleotide research. Nalgene recommends autoclaving to destroy DNase and offers further techniques to inhibit or remove RNase from their plastic containers.

Available bottle weights include light weight economy, standard weight laboratory quality, or high density packaging bottles.

The Nalgene manufacturing facilities are ISO 13485:2003 registered and their containers meet RoHS and USP Class VI standards.